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. 2022 Jun 8:1–37. Online ahead of print. doi: 10.1007/s10479-022-04753-w

Table 1.

Some major epidemics/pandemics across the world

Years/Duration Name of the Epidemics/pandemics Causes Death (Approx) Region References
2019- present COVID-19 Coronavirus 4.51 M Worldwide Worldometers (2021)
1981-present HIV/AIDS Virus/Chimpanzees 25–35 M Worldwide Pandey and Galvani (2019)
1968–1969 Hong Kong Flu Influenza A/H3N2 1–4 M Worldwide Akin and Gözel (2020)
1918–1920 Spanish flu Influenza A/H1N1 40–50 M Worldwide Antonovics et al. (2006)
1519–1520 Mexico smallpox Smallpox 5–8 million Mexico Acuña-Soto et al. (2002)
1346–1353 Black Death Bubonic plague 75–200 M Europ, Asia, North America DeWitte (2014)
541–549 Plague of Justinian Influenza A/H1N1 15–100 M Europe and West Asia Mordechai et al. (2019)
165–180 Antonine Plague Smallpox or measles 5–10 M Roman Empire Yapijakis (2009)