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. Author manuscript; available in PMC: 2022 Jun 8.
Published in final edited form as: ACS Biomater Sci Eng. 2022 Mar 31;8(4):1686–1695. doi: 10.1021/acsbiomaterials.2c00043

Figure 5.

Figure 5.

One-compartment pharmacokinetic behavior for 2 and 3 (A, B) and 5 μm diameter MBs (C) administered at low MVDs. Solid lines represent a mono-exponential decay fit with R2 ≥ 0.97. *p ≤ 0.05 vs. 5 MVD and $p < 0.05 vs. 10 MVD between same timepoints, top symbols represent the comparison of 20 MVD vs 10 and 5 MVD, whereas bottom symbols represent the comparison of 10 MVD vs 5 MVD. p values were obtained from unpaired t-test comparison. The first point in each curve represents the initial MVD injected, and the corresponding time was calculated theoretically using the model fit. Data represents the mean ± standard deviation for three different experiments.