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. 2022 May 24;4(3):fcac133. doi: 10.1093/braincomms/fcac133

Figure 3.

Figure 3

DMXAA preconditioning increases antiviral interferon response gene expression in vivo. qPCR analysis of Ifit1(A–D) gene expression with 25 mg/kg DMXAA in a time-dependent manner, in mice brain, liver, spleen, and kidney. The repeated measures one-way ANOVA with Dunnett's multiple comparisons test revealed significant effects for the time (Brain: F(1.030, 3.091) = 11.96, P = 0.0387; Liver: F(1.035, 3.105) = 42.77, P = 0.0065; Kidney: F(1.003, 3.009) = 13.22, P = 0.0356; Spleen: F(1.029, 3.008) = 23.71, P = 0.0154). Data are expressed as mean ± SD (n = 3). ****P < 0.0001, **P < 0.01, *P < 0.05 compared with the control group.