Table 2.

Overview of binding parameters of UR-CG072 and UR-MK342.

	method	Kd (nM) ± s.e.m.	kon (nM−1 min−1) ± s.e.m.	koff (min−1) ± s.e.m.
UR-CG072	FA equilibrium	3.6 ± 1.1
	FA kinetic SB toolbox	8.5 ± 0.8	0.0017 ± 0.0002	0.015 ± 0.002
	microscopy saturation	2.85 ± 0.10
	microscopy kinetic	2.6 ± 0.7	0.017 ± 0.007	0.046 ± 0.004
	radioligand displacement (Ki)	3.7 ± 0.6 [16]
UR-MK342	FA equilibrium	1.2 ± 0.5
	FA kinetic SB toolbox	1.3 ± 0.4	0.0028 ± 0.0010	0.0037 ± 0.0012
	radioligand displacement (Ki)	0.97 ± 0.07 [16]