Table 1.

Observed ICP-MS quantification of Pt in DRG by route of administration.

DRG Pt concentrations	IP (ppm)			IV (ppm)_
Time point	Mean	Std. Dev.	SEM	Mean	Std. Dev.	SEM
5 (min)	4.65	6.01	2.13	0.422	0.44	0.17
30 (min)	6.57	4.07	1.43	1.62	1.00	0.35
60 (min)	11.75	5.85	2.07	3.65	2.51	0.89
120 (min)	9.62	4.61	1.63	14.29	8.03	2.84
180 (min)	12.22	6.17	2.18	12.95	6.83	2.42
240 (min)	12.15	8.81	3.11	20.326	12.47	4.41
72 (hrs) (long-term)	1.58	1.40	0.53	5.56	3.64	1.38

Acute and long-term pattern of platinum distribution in dorsal root ganglia. Average platinum concentration (n = 4 rats per experimental group) with two biologic replicates each at all the observed time points (n = 7).