Table 2.

Summary of In-hospital Outcomes Comparing HCR and CABG

Subgroup	No. of studies	OR	95%CI	p	I2 (%)	Effect-model
MACCE	6	0.90	0.54–1.48	0.67	0	Fixed
ICU LOS	9	− 13.34	− 20.27 to (− 6.41)	< 0.001	95	Random
Ventilation time	5	− 8.69	− 17.74 to 0.36	0.06	97	Random
Major bleeding	2	0.36	0.11–1.22	0.10	58	Fixed
Return to work	2	− 68.26	− 77.99 to (− 58.53)	< 0.001	0	Fixed
Atrial fibrillation	8	0.58	0.36–0.93	0.02	56	Random
Infection	6	0.24	0.09–0.64	0.004	1	Fixed
cTnI	3	− 0.39	− 1.06 to 0.27	0.25	83	Random
25% increase in creatinine	2	0.88	0.55–1.39	0.57	0	Fixed
Cerebrovascular accidents	2	0.87	0.21–3.65	0.85	42	Fixed
Mechanical ventilation > 24 h	5	0.49	0.32–0.76	0.001	31	Fixed
Any transfusion of packed red blood cells	10	0.38	0.28–0.51	< 0.001	58	Random
Neurologic event	2	1.24	0.15–10.53	0.84	0	Fixed
Renal failure	7	0.72	0.40–1.31	0.29	51	Random
Operation time	3	− 27.86	− 109.08 to 52.37	0.50	99	Random
Extubation in operating room	2	0.13	0.04–0.41	< 0.001	0	Fixed
Death	8	1.65	0.90–3.02	0.11	0	Fixed
Myocardial infarction	12	0.77	0.45–1.30	0.32	0	Fixed
Pleural effusion	2	0.44	0.20–0.97	0.04	0	Fixed
Repeat revascularization	6	3.50	2.07–5.94	< 0.001	0	Fixed
Hemodialysis	3	0.3	0.05–1.75	0.18	0	Fixed
Platelet transfusion	2	0.41	0.18–0.91	0.03	0	Fixed
Major complications	3	0.40	0.16–1.03	0.06	61	Random
Reopening for bleeding	8	1.11	0.80–1.53	0.53	0	Fixed
Stroke	7	0.92	0.44–1.94	0.84	0	Fixed
Hospital length of stay	11	− 1.62	− 2.38 to (− 0.85)	< 0.001	87	Random

HCR, hybrid coronary revascularization; CABG, coronary artery bypass grafting; OR, odds ratio; CI, confidence interval; MACCE,major adverse cardiac or cerebrovascular events; ICU LOS, intensive care unit length of stay

The effect measure is standard mean difference (SMD): cTnI. The effect measure is weighted mean difference (WMD): ICU LOS; Ventilation time; Return to work; Operation time; Hospital length of stay