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. Author manuscript; available in PMC: 2023 Feb 1.
Published in final edited form as: Acc Chem Res. 2022 Jan 11;55(3):309–318. doi: 10.1021/acs.accounts.1c00560

Figure 1.

Figure 1.

Representative biomolecules/entities that are capable of autonomously translocating across the plasma or endosomal membrane of a cell. (a) Linear CPP Tat;4 (b) cyclic CPP12;1 (c) non-peptidic CPM3;5 (d) IL-1β 55 (PDB: 31BI); (e) diphtheria toxin39 (PDB: 1xdt); (f) a cell-permeable antibody;52,53 (g) adenovirus;8 (h) polyethyleneimine;9 and (i) a lipid nanoparticle.10