Table 1.
Summary of Schlafen 11 (SLFN11) expression in non-tumors and tumors
| Organ and diagnosis | Number | 1+ | 2+ | 3+ | SLFN11 (+) n (%) |
|---|---|---|---|---|---|
|
| |||||
| Brain | |||||
| Normal | 15 | 7 | 8 | 0 | 15 (100) |
| Meningioma | 20 | 0 | 3 | 17 | 20 (100) |
| Schwannoma | 6 | 0 | 0 | 6 | 6 (100) |
| Glioblastoma | 30 | 2 | 8 | 10 | 20 (67) |
| Lung | |||||
| Alveolar epithelium | 31 | 8 | 12 | 11 | 31 (100) |
| Glandular epithelium | 31 | 8 | 7 | 9 | 24 (77) |
| Squamous cell carcinoma | 31 | 5 | 3 | 4 | 12 (42) |
| Adenocarcinoma | 30 | 4 | 3 | 11 | 18 (40) |
| Breast | |||||
| Normal | 32 | 1 | 0 | 0 | 1 (3) |
| Invasive ductal carcinoma | 35 | 4 | 6 | 7 | 17 (49) |
| Invasive lobular carcinoma | 16 | 3 | 1 | 0 | 4 (25) |
| Esophagus | |||||
| Normal | 34 | 21 | 10 | 0 | 31 (91) |
| Squamous cell carcinoma | 34 | 10 | 10 | 8 | 28 (82) |
| Stomach | |||||
| Normal | 40 | 8 | 6 | 4 | 18 (45) |
| Adenocarcinoma | 40 | 4 | 11 | 11 | 26 (65) |
| Colon | |||||
| Normal | 39 | 0 | 0 | 0 | 0 (0) |
| Adenocarcinoma | 39 | 0 | 0 | 0 | 0 (0) |
| Liver | |||||
| Normal | 31 | 15 | 9 | 0 | 24 (77) |
| Hepatocellular carcinoma | 31 | 9 | 9 | 4 | 22 (71) |
| Bile duct | |||||
| Normal | 20 | 6 | 2 | 0 | 8 (40) |
| Adenocarcinoma | 20 | 8 | 1 | 0 | 9 (45) |
| Pancreas | |||||
| Normal | 34 | 0 | 0 | 0 | 0 (0) |
| Adenocarcinoma | 34 | 3 | 4 | 1 | 8 (24) |
| Kidney | |||||
| Normal | 44 | 44 | 0 | 0 | 44 (100) |
| Clear cell renal cell carcinoma | 41 | 4 | 13 | 20 | 37 (98) |
| Papillary renal cell carcinoma | 9 | 2 | 0 | 0 | 2 (22) |
| Chromophobe renal cell carcinoma | 6 | 0 | 0 | 0 | 0 (0) |
| Urinary bladder | |||||
| Normal | 30 | 0 | 0 | 0 | 0 (0) |
| Invasive urothelial carcinoma | 34 | 13 | 7 | 3 | 23 (68) |
| Prostate | |||||
| Normal | 32 | 0 | 0 | 0 | 0 (0) |
| Adenocarcinoma | 32 | 1 | 0 | 0 | 1 (3) |
| Uterine cervix | |||||
| Squamous epithelium | 16 | 5 | 7 | 2 | 14 (89) |
| Glandular epithelium | 13 | 5 | 2 | 4 | 11 (69) |
| Squamous cell carcinoma | 20 | 1 | 4 | 10 | 15 (75) |
| Adenocarcinoma | 13 | 1 | 3 | 5 | 9 (75) |
| Uterine corpus | |||||
| Normal | 30 | 13 | 1 | 0 | 14 (85) |
| Endometrioid carcinoma | 26 | 4 | 6 | 8 | 18 (69) |
| Serous carcinoma | 4 | 0 | 2 | 1 | 3 (75) |
| Ovary | |||||
| Fallopian tube | 15 | 9 | 5 | 1 | 15 (100) |
| Serous carcinoma | 18 | 1 | 5 | 6 | 12 (67) |
| Clear cell carcinoma | 7 | 1 | 2 | 3 | 6 (86) |
| Endometrioid carcinoma | 3 | 0 | 0 | 2 | 2 (67) |
| Mucinous carcinoma | 9 | 1 | 2 | 0 | 3 (33) |
| Bone and soft tissue | 31 | 3 | 7 | 13 | 23 (74) |
| Osteosarcoma | 6 | 0 | 0 | 4 | 4 |
| Chondrosarcoma | 1 | 0 | 0 | 0 | 0 |
| Leiomyosarcoma | 5 | 1 | 2 | 1 | 4 |
| Liposarcoma | 9 | 0 | 3 | 4 | 7 |
| Myxofibrosarcoma | 4 | 0 | 1 | 3 | 4 |
| Spindle cell sarcoma | 2 | 1 | 0 | 0 | 1 |
| Pleomorphic sarcoma | 1 | 0 | 0 | 1 | 1 |
| Synovial sarcomas | 2 | 0 | 1 | 0 | 1 |
| Clear cell sarcoma | 1 | 1 | 0 | 0 | 1 |