FIGURE 1.

The ligand‐binding patterns of the seven‐transmembrane domain G‐protein‐coupled chemokine receptors. The receptors CCR1–CCR5, CCR7, CCR8, CCR10, CXCR1–CXCR3, and CXCR7 all bind to multiple chemokines. In contrast, CCR6, CCR9, CXCR4–CXCR6, CX3CR1, and XCR1 each bind only one ligand. Four molecules are included in the atypical chemokine receptor (ACKR) family and boast high affinity to CC‐/CXC‐ chemokines (the figure was created using biorender.com)