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. 2022 Apr 5;11(3):e210130. doi: 10.1530/ETJ-21-0130

Table 1.

Demographic, clinical, and biochemical parameters of all patients developing PoSH and comparison of those who did or did not achieve remission at 6 months.

Overall (n  =270) Recovery within 6 months (n  = 136) PoSH at 6 months (n  = 54) P value
Median age (IQR) 45.2 (32–57.6) 46.3 (33.9–57.6) 41.7 (28.9–59.9) 0.411
Gender, F/M 215/55 111/25 46/8 0.556
Pre-op diagnosis, % (n)
 Cancer/suspected cancer 36.3% (98) 38.2% (52) 42.6% (23) 0.739
 Hyperthyroidism 41.9% (113) 40.4% (55) 40.7% (22)
 Thyroid nodule 21.9% (59) 21.3% (29) 16.7% (9)
Pathology % (n)
 Benign 64.4% (174) 62.5% (85) 57.4% (31) 0.516
 Malignant 35.6% (96) 37.5% (51) 42.6% (23)
Type of surgery, % (n)
 CT 4.1% (11) 4.4% (6) 1.9% (1) 0.783
 CT+CND 2.6% (7) 2.9% (4) 3.7% (2)
 TT 71.5% (193) 69.1% (94) 66.7% (36)
 TT+CND 21.9% (59) 23.5% (32) 27.8% (15)
Adjusted calcium day 1 (mmol/L) (IQR) (n) 2.05 (1.98–2.09) (n  =269) 2.06 (1.99–2.1) (n  =136) 1.99 (1.90–2.07) (n  =54) 0.002
PTH day 1 (pmol/L) (IQR) (n) 2.0 (1.0–3.3) (n  = 190) 2.3 (1.4–3.5) (n  = 113) 0.8 (0.5–1.2) (n  = 39) <0.001

CND, central node dissection; CT, completion thyroidectomy; F/M, female/male; IQR, inter-quartile range; PoSH, post-surgical hypoparathyroidism; PTH, parathyroid hormone; TT, total thyroidectomy.