Table 1.
Demographic, clinical, and biochemical parameters of all patients developing PoSH and comparison of those who did or did not achieve remission at 6 months.
| Overall (n =270) | Recovery within 6 months (n = 136) | PoSH at 6 months (n = 54) | P value | |
|---|---|---|---|---|
| Median age (IQR) | 45.2 (32–57.6) | 46.3 (33.9–57.6) | 41.7 (28.9–59.9) | 0.411 | 
| Gender, F/M | 215/55 | 111/25 | 46/8 | 0.556 | 
| Pre-op diagnosis, % (n) | ||||
| Cancer/suspected cancer | 36.3% (98) | 38.2% (52) | 42.6% (23) | 0.739 | 
| Hyperthyroidism | 41.9% (113) | 40.4% (55) | 40.7% (22) | |
| Thyroid nodule | 21.9% (59) | 21.3% (29) | 16.7% (9) | |
| Pathology % (n) | ||||
| Benign | 64.4% (174) | 62.5% (85) | 57.4% (31) | 0.516 | 
| Malignant | 35.6% (96) | 37.5% (51) | 42.6% (23) | |
| Type of surgery, % (n) | ||||
| CT | 4.1% (11) | 4.4% (6) | 1.9% (1) | 0.783 | 
| CT+CND | 2.6% (7) | 2.9% (4) | 3.7% (2) | |
| TT | 71.5% (193) | 69.1% (94) | 66.7% (36) | |
| TT+CND | 21.9% (59) | 23.5% (32) | 27.8% (15) | |
| Adjusted calcium day 1 (mmol/L) (IQR) (n) | 2.05 (1.98–2.09) (n =269) | 2.06 (1.99–2.1) (n =136) | 1.99 (1.90–2.07) (n =54) | 0.002 | 
| PTH day 1 (pmol/L) (IQR) (n) | 2.0 (1.0–3.3) (n = 190) | 2.3 (1.4–3.5) (n = 113) | 0.8 (0.5–1.2) (n = 39) | <0.001 | 
CND, central node dissection; CT, completion thyroidectomy; F/M, female/male; IQR, inter-quartile range; PoSH, post-surgical hypoparathyroidism; PTH, parathyroid hormone; TT, total thyroidectomy.
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