Table 2.

Comparison of demographic, clinical, and biochemical parameters between those who did or did not achieve remission beyond 6 months.

	Late recovery (beyond 6 months) (n  = 19)	Persistent PoSH without evidence of late recovery (n  = 35)	P value
Median age (IQR)	39.6 (27.2–51.9)	47.3 (29.5–68.9)	0.113
Gender F/M	18/1	28/7	0.145
Pre-op diagnosis % (n)
Cancer/suspected cancer	31.6% (6)	48.6% (17)	0.393
Hyperthyroidism	52.6% (10)	34.3 % (12)
Thyroid nodule	15.8% (3)	17.1% (6)
Pathology, % (n)
Benign	68.4% (13)	51.4% (18)	0.228
Malignant	31.6% (6)	48.6% (17)
Type of surgery, % (n)
CT	0%	2.9% (1)	0.600
CT+CND	0%	5.7% (2)
TT	73.7% (14)	62.9% (22)
TT+CND	26.3% (5)	28.6% (10)
Adjusted calcium day 1 (mmol/L) (IQR) (n)	1.95 (1.84-2.05) (n  = 19)	2.01 (1.93-2.08) (n  = 35)	0.198
Adjusted calcium day 2 to 2 weeks (mmol/L) (IQR) (n)	1.93 (1.85–2.02) (n  = 19)	1.99 (1.90–2.15) (n  =34)	0.185
Adjusted calcium 2 weeks to 3 months (mmol/L) (IQR) (n)	2.23 (2.13–2.31) (n  =18)	2.18 (2.0– 2.27) (n  =34)	0.240
Adjusted calcium 3–6 months (mmol/L) (IQR) (n)	2.20 (2.11–2.22) (n  = 16)	2.19 (2.02–2.26) (n  = 31)	0.928
Adjusted calcium >6 months (mmol/L) (IQR) (n)	2.17 (2.07–2.26) (n  = 16)	2.09 (1.97–2.18) (n  = 31)	0.048
PTH day 1 (pmol/L) (IQR) (n)	0.9 (0.7–1.4) (n  = 13)	0.8 (0.5–1.0) (n  = 26)	0.435
PTH day 2 to 2 weeks (pmol/L) (IQR) (n)	0.8 (0.5–1.6) (n  = 16)	0.9 (0.6–1.2) (n  =27)	0.554
PTH 2 weeks to 3 months (pmol/L) (IQR) (n)	2.2 (1.5–3.6) (n  = 15)	1.4 (0.8–2.2) (n  = 28)	0.072
PTH 3–6 months (pmol/L) (IQR) (n)	2.3 (1.8–3.8) (n  =14)	1.8 (0.8–2.5) (n  = 23)	0.071
PTH ≥6 months (pmol/L) (IQR) (n)	2.6 (2.3–3.0) (n  = 15)	1.8 (1.2–3.0) (n  = 25)	0.016
PTH ≥1.6 pmol/L at >6 months	15/15	16/25	0.008
Magnesium day 1 (mmol/L) (IQR) (n)	0.68 (0.57–0.69) (n  = 6)	0.71 (0.67–0.77) (n  =13)	0.127
Magnesium day 2 – 2 weeks (mmol/L) (IQR) (n)	0.66 (0.59–0.75) (n  = 6)	0.74 (0.68–0.79) (n  = 19)	0.198
Magnesium 2 weeks to 3 months (mmol/L) (IQR) (n)	0.77 (0.71–0.81) (n  = 6)	0.8 (0.76–0.84) (n  = 19)	0.246
Magnesium 3–6 months (mmol/L) (IQR) (n)	0.81 (0.75–0.86) (n  = 6)	0.8 (0.76–0.87) (n  = 17)	1.0
Magnesium >6 months (mmol/L) (IQR) (n)	0.82 (0.76–0.87) (n  = 11)	0.8 (0.76–0.85) (n  = 29)	0.720
Creatinine at surgery (µmol/L) (IQR) (n)	63 (52–78) (n  = 19)	67 (55–80) (n  = 34)	0.388
Creatinine >6 months (µmol/L) (IQR) (n)	70 (62–78) (n  = 19)	72 (64–85) (n  = 34)	0.220

CND, central node dissection; CT, completion thyroidectomy; F/M, female/male; IQR, inter-quartile range; PoSH, post-surgical hypoparathyroidism; PTH, parathyroid hormone; TT, total thyroidectomy.