Table 3.

Correlations between LEAP2, ghrelin, ghrelin/LEAP2 with age, BMI, glucose, insulin, HOMA-IR, HbA1c, total cholesterol, HDL-C, LDL-C, and TG in all the subjects, in healthy adults, and in diabetics (n  = 27, 29).

	Group	Ghrelin	LEAP2	Ghrelin/LEAP2
Age (years)	All	−0.106	0.398	−0.385
	Normal	−0.093	0.325	−0.362
	T2D	0.044	0.371	−0.310
BMI (kg/m2)	All	0.082	0.051	−0.075
	Normal	0.228	0.181	0.008
	T2D	−0.163	0.021	−0.290
Glucose (mmol/L)	All	−0.145	0.230	−0.318
	Normal	0.293	−0.144	0.210
	T2D	0.082	0.028	−0.110
Insulin (µIU/mL)	All	0.061	−0.058	−0.043
	Normal	0.4791	0.1151	0.1852
	T2D	−0.075	−0.141	−0.089
HOMA-IR	All	−0.082	0.085	−0.236
	Normal	0.489	0.063	0.203
	T2D	−0.037	−0.107	−0.129
HbA1c (%)	All	−0.218	0.376	−0.459
	Normal	0.017	0.224	−0.148
	T2D	0.281	0.141	−0.105
Total cholesterol (mg/dL)	All	−0.008	0.198	−0.162
	Normal	−0.056	0.585	−0.477
	T2D	−0.052	0.180	−0.059
HDL-C (mg/dL)	All	0.226	−0.044	0.214
	Normal	0.214	0.131	0.157
	T2D	−0.079	0.195	−0.300
LDL-C (mg/dL)	All	−0.151	0.171	−0.377
	Normal	0.014	0.537	−0.451
	T2D	−0.313	−0.116	0.003
TG (mg/dL)	All	0.087	−0.032	0.016
	Normal	0.067	0.158	−0.128
	T2D	0.174	−0.087	0.179

Bold values are statistically significant (P < 0.05).

HOMA-IR, Homeostatic Model Assessment for Insulin Resistance; HbA1c, hemoglobin A1c; TG, triglycerides; T2D, type 2 diabetes.