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Bioluminescence rhythms of Bmal1 and Per2 promoter activities following cytokine treatments in RAW 264.7-Bmal1:luc and –Per2:luc cells. Shown are raw (A,B) and detrended, smoothed (C,D) time series averaged across replicates (N = 8) for each treatment. The standard error is shown with a light envelope around the mean; in some instances, this is too small to be visualized. The raw and detrended data with individual replicates can be found in Fig. S3 and S4, respectively.
