TABLE 3.

Characteristics of MM patients when SRE occurred

No.	Age/Sex	Amyloidosis	Details of SRE	Treatment response	Triggers	Complications/Comorbidities	PS (ECOG)
1	76/M	None	Femoral fracture	SD	Loss of balance Falling down	Peripheral neuropathy	2
2	47/M	None	Rib fracture Spinal cord compression	PD	None	None	2
3	56/M	None	Pelvic fracture	PD	Loss of balance Falling down	DM type 2 Orthostatic hypotension	4
4	55/M	None	Vertebral fracture Spinal cord compression	PD	None	Peripheral neuropathy	4
5	78/M	None	Sacral fracture Spinal cord compression	PD	None	None	3
6	77/M	None	Vertebral fracture Rib fracture	PD	None	DM type 2 Orthostatic hypotension	1
7	74/F	None	Vertebral fracture	PD	Loss of balance	Peripheral neuropathy	3
8	80/F	None	Vertebral fracture	PD	None	DM type 2 Muscle weakness	3
9	73/F	Heart, Tongue, Skin	Femoral fracture	VGPR	Falling down	Muscle weakness Orthostatic hypotension	2
10	78/F	GI tract, Skin, Muscle	Vertebral fracture	VGPR	Loss of balance Falling down	Muscle weakness	1
11	70/M	Heart, Kidney, GI tract	Rib fracture	VGPR	Falling down	DM type 2 Peripheral neuropathy Orthostatic hypotension	0

DM, diabetes mellitus; ECOG, Eastern Cooperative Oncology Group; F, female; GI tract, gastrointestinal tract; M, male; PD, progressive disease; PS, performance status; SD, stable disease, VGPR, very good partial response.