FIGURE 5.

Median changes in HRQoL scores over time in patients with CLL receiving LOT1 by treatment regimen for (A) FACT‐Leu Total scores and (B) EQ‐5D‐3L index. A, Higher FACT‐Leu total scores indicate better HRQoL. B, Higher EQ‐5D index scores indicate better HRQoL. Abbreviations: BR, bendamustine and rituximab; CLL, chronic lymphocytic leukemia; EQ‐5D‐3L, EuroQol 5‐dimension 3‐level questionnaire; FACT‐Leu, Functional Assessment of Cancer Therapy–Leukemia; FCR, fludarabine, cyclophosphamide, and rituximab; HRQoL, health‐related quality of life; LOT1, first‐line therapy; R‐mono, rituximab monotherapy