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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Neuropharmacology. 2022 Mar 25;210:109046. doi: 10.1016/j.neuropharm.2022.109046

Fig. 3.

Fig. 3.

Effects of CP154,526 (CP), TCS1102 (TCS), and CP154,526+TCS1102 (CP+TCS) on the stress-induced reinstatement of alcohol-seeking behavior. (A) Intermittent footshock stress precipitated alcohol-seeking behavior in rats that received vehicle (VEH). The administration of CP154,526 in the IL prevented the stress-induced reinstatement of alcohol seeking, an effect that was blocked by the co-administration of CP154,526+TCS1102. The administration of CP154,526 in the PL had no effect on the stress-induced reinstatement of alcohol-seeking behavior. (B) Co-administration of CP154,256 and TCS1102 increased inactive lever responses following administration in the IL. The data are expressed as mean + SEM. +p < 0.05, vs. respective sham injection; *p < 0.05, vs. VEH.