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. 2022 Jun 4;15:5455–5463. doi: 10.2147/IJGM.S368344

Table 1.

Univariate Analysis of Differences in Nodule Type, Demographic Differences and CT Features Between the Invasive Mucinous Adenocarcinoma and Invasive Non-Mucinous Lung Adenocarcinoma Groups

IMA (N=53) INMA (N=141) Statistic P
Sex 1.47 0.225
M 25 (47.17) 53 (37.59)
F 28 (52.83) 88 (62.41)
Age (years) 70.89±14.50 58.52±9.57 5.76 0*
Nodule type 0a
I 44 (83.02) 92 (65.25)
II 9(16.98) 49 (34.75)
Size (cm) 1.80±0.73 1.44±0.59 0.002**
Morphology Clearly irregular 8 (15.09) 14 (9.92) 1.022 0.312
Spherical or spheroid 45 (84.91) 127 (90.08)
Tumor lung interface Indistinct 13 (24.53) 3 (2.13) 22.669 0
Distinct 40 (75.47) 138 (97.87)
Lobulation Yes 32 (60.38) 61 (43.26) 4.521 0.033
No 21 (39.62) 80 (56.74)
Spiculation Yes 31 (58.49) 54 (38.3) 6.38 0.012
No 22 (41.51) 87 (61.7)
Air bronchogram or vacuolar sign Yes 34 (64.15) 34 (24.11) 27.124 0
No 19 (35.85) 107 (75.89)
Abnormal vascular changes Yes 41 (77.36) 129 (91.49) 7.095 0.008
No 12 (22.64) 12 (8.51)
Pleural retraction Yes 33 (62.26) 79 (56.03) 0.614 0.433
No 20 (33.74) 62 (43.97)

Notes: *Normal distribution (unpaired t-test) with statistical significance (P<0.05); **non-normal distribution (Mann–Whitney U-test) with statistical significance (P<0.05); afisher exact test. Bold values referred to significant variables (p < 0.05) in univariate analysis.