Table 1.

Inclusion and Exclusion Criteria.

INCLUSION CRITERIA	EXCLUSION CRITERIA
Endpoint criteria
Acute myeloid leukemia Bladder malignancy Cardiac toxicity Cataracts Clinical leukoencephalopathy Dental abnormalities Hepatic dysfunction Impaired spermatogenesis Myelodysplasia Neurocognitive deficits Osteonecrosis (avascular necrosis) Ovarian hormone deficiencies Pulmonary fibrosis Pulmonary toxicity Reduced bone mineral density (BMD) Reduced ovarian follicular pool Renal toxicity Sinusoidal obstruction syndrome (SOS) Urinary tract toxicity Adverse psychosocial/quality of life effects Mental health disorders Fatigue Sleep problems Socioeconomic issues Psychosocial disability due to pain Peripheral sensory neuropathy	Limitations in healthcare and insurance access Ototoxicity Risky behaviors (i.e. alcohol use)
Research concept-related criteria
Publications assessing long-term adverse events in the context of CHOP and its components	Publications not assessing long-term adverse events in the context of CHOP and its components
Study countries and publication year
All	All
Publication language
English; foreign language papers with English abstracts	Foreign language publications
Publication type and study design
Randomized controlled trials (n > 100) Observational study (n > 100) Cross-sectional study (n > 100) Systematic review Case series (n > 20)	News Video-audio media Webcast Case reports Case series (n < 20) Letter Commentary Review Treatment/practice guidelines Consensus development Note RCT, observational study, or cross-sectional study with n < 100