Table 4.
Virus | Mean titer (log 10 PFU/ml or g) a | |||||
---|---|---|---|---|---|---|
Nasal turbinates | Soft palate | Trachea | Lung | Olfactory bulb | Brain | |
A/Alberta/1/2020 | 2.9 ± 0.7 (3/3) | 3.3 ± 0.6 (3/3) | 2.62 (1/3) | 2.6 ± 1.1 (2/3) | ND (0/3) | ND (0/3) |
A/Ohio/24/2017 | 4.4 ± 0.3 (3/3) | 4.3 ± 0.1 (3/3) | 4.4 ± 1.0 (2/3) | 3.8 ± 0.7 (3/3) | ND (0/3) | ND (0/3) |
A/California/62/2018 | 4.9 ± 0.5 (3/3) | 5.5 ± 0.7 (3/3) | 4.2 ± 0.6 (3/3) | 3.1 ± 0.7 (3/3) | ND (0/3) | ND (0/3) |
A/Michigan/288/2019 | 5.4 ± 0.1 (3/3) | 5.1 ± 0.5 (3/3) | 5.9 ± 0.3 (3/3) | 4.8 ± 0.5 (3/3) | 2.4 ± 0.6 (3/3) | ND (0/3) |
A/Michigan/45/2015 | 5.4 ± 0.3 (3/3) | 3.0 ± 1.1 (3/3) | 4.1 ± 0.4 (3/3) | 3.2 (1/3) | ND (0/3) | ND (0/3) |
A/Idaho/7/2018 | 4.0 ± 0.6 (3/3) | 1.8 (1/3) | 1.8 (1/3) | ND b (0/3) | 3.9 (1/3) | ND (0/3) |
A/Nebraska/14/2019 | 5.7 ± 0.1 (3/3) | 5.1 ± 0.7 (3/3) | 4.7 ± 0.6 (3/3) | 4.4 ± 1.5 (3/3) | 3.8 ± 2.0 (3/3) | 2.5 ± 1.3 (3/3) |
Mean virus titer in tissues collected on day 3 post inoculation ± SD. Nasal turbinate viral titers are presented as log10 PFU/ml and trachea and soft palate, trachea, lung, olfactory bulb, and brain titers are presented as log10 PFU/g of tissue. Number of ferrets with detectable titers are indicated in parenthesis.
ND – not detected.