Figure 4.

Enhanced serum neutralization against D614G and omicron pseudotyped virus by C4-1. The indicated pseudotyped viruses were incubated with dilutions of serum derived from individuals vaccinated with Rong'an vaccine or vaccine C4-1/serum mixture (a) and serum from COVID-19 patients or patients convalescent C4-1/serum mixture (b). The lines indicate the geometric mean ID ${}_{50}$. The limit of ID ${}_{50}$ detection was >30. Paired t-test was used to analyse differences between groups. ***p<0.001. Data are mean ±SEM, n = 2 replicates.