Skip to main content
. 2022 Jun 8;17(6):e0267554. doi: 10.1371/journal.pone.0267554

Table 2. Descriptive statistics of categorical variables for clinical pregnancy and non-clinical pregnancy groups.

N = 17,288 Pregnancy
(N = 6,548)
No pregnancy p-value
(N = 10,740)
N Percentage N Percentage
Female age group ***
 <30 years 294 4.49 267 2.49
 30~34 years 1903 29.06 2091 19.47
 35~39 years 3124 47.71 4425 41.20
 >40 years 1227 18.74 3957 36.84
Cause of infertility ***
 Tubal factor 902 13.78 1335 12.43
 Ovary factor 607 9.27 826 7.69
 Endometriosis 691 10.55 1037 9.66
 Uterine factor (myoma adenomyosis, uterine synechia) 306 4.67 454 4.23
 Others (other female factors) 2078 31.73 3962 36.89
 Male factor 985 15.04 1311 12.21
 Either two factors 940 14.36 1779 16.56
 Unexplained 39 0.60 36 0.34
Oocyte retrieval **
 Yes 4416 67.44 7412 69.01
 No 2132 32.56 3328 30.99
Artificially assisted reproductive method
 IVF/ET 6544 99.94 10,739 99.99
 ZIFT/TET 4 0.06 1 0.01
Fertilization method ***
 ICSI 4375 66.81 7352 68.45
 Assisted hatching 223 3.41 226 2.10
 ICSI and assisted hatching 13 0.20 27 0.25
 PGS 121 1.85 117 1.09
 PGD 0 0.00 0 0.00
 No Use 1760 26.88 2943 27.40
 Others 56 0.86 75 0.70
Source of sperm and oocytes
 Without donation 6445 98.43 10,596 98.66
 Oocyte donation 75 1.15 93 0.87
 Sperm donation 28 0.43 51 0.47
The use of fresh/freeze-thaw **
 Fresh 4406 67.29 7456 69.42
 Frozen 2142 32.71 3284 30.58
Ovarian hyperstimulation syndrome ***
 None 6323 96.56 10,526 98.01
 Mild 218 3.33 212 1.97
 Moderate 6 0.09 1 0.01
 Severe 1 0.02 1 0.01
Ovarian stimulation protocol ***
 Natural cycle (including frozen-embryo transfer cycle) 2132 55.84 3328 54.51
 Oral stimulation drug 0 0.00 3 0.05
 Short protocol 248 6.50 442 7.24
 Long protocol 306 8.01 356 5.83
 Ultra-long protocol 124 3.25 165 2.70
 Antagonist protocol 1006 26.35 1803 29.53
 Others 2 0.05 8 0.13

* p < 0.05,

** p < 0.01,

*** p < 0.001 by a chi-squared test for categorical variables.

IVF/ET, in vitro fertilization/embryo transfer; ZIFT/TET, zygote intrafallopian transfer/tubal embryo transfer; ICSI, intracytoplasmic sperm injection; PGS, preimplantation genetic screening; PGD, preimplantation genetic diagnosis.