Table 5.
Significant CNV loss regions called by GISTIC across all 17 samples submitted for whole-exome sequencing. GISTIC is an algorithm which identifies regions of the genome that are gained or lost more than expected by chance across a set of samples.
| Cytoband | 1p36.13 | 7q22.1 | 12q12 | 2q11.1 | 19q13.2 | 17p11.2 | 1q21.3 | 17q21.2 |
|---|---|---|---|---|---|---|---|---|
| q value | 2.21E-08 | 2.21E-08 | 2.21E-08 | 2.95E-05 | 0.001411 | 0.0016159 | 0.0019967 | 0.054262 |
| Residual q value | 2.21E-08 | 2.21E-08 | 2.21E-08 | 2.95E-05 | 0.001411 | 0.0016159 | 0.0019967 | 0.054262 |
| Wide peak boundaries | chr1:16903823-16913583 | chr7:100638857-100642454 | chr12:40879121-40897247 | chr2:96604592-96606984 | chr19:40368281-40373890 | chr17:21217587-21318587 | chr1:151862662-152285860 | chr17:39253750-39432561 |
| Genes in wide peak | NBPF1 | MUC12 | [LRRK2] | [LOC729234] | FCGBP | KCNJ12 | FLG | KRTAP9-9 |
| MAP2K3 | S100A10 | KRTAP4-6 | ||||||
| KCNJ18 | S100A11 | KRTAP4-12 | ||||||
| TCHH | KRTAP9-2 | |||||||
| THEM4 | KRTAP9-3 | |||||||
| TCHHL1 | KRTAP9-8 | |||||||
| RPTN | KRTAP4-4 | |||||||
| HRNR | KRTAP9-4 | |||||||
| KRTAP4-1 | ||||||||
| KRTAP4-5 | ||||||||
| KRTAP4-3 | ||||||||
| KRTAP4-2 | ||||||||
| KRTAP4-11 | ||||||||
| KRTAP4-8 | ||||||||
| KRTAP9-1 | ||||||||
| KRTAP4-9 |