Figure 6. Effect of IL-15 and IFN-α in the natural killer (NK) function.

CD4⁺ T cells from ART-suppressed participants coated with a gp120 recombinant protein were subjected to antibody-dependent cell cytotoxicity (ADCC) assays in the presence of cytokines. The graph shows the percentage of ADCC killing of HIVgp120-coated CD4⁺ T cells by autologous NK cells after treatment with IL-15 or IFN-α. Statistical comparisons were performed using the Wilcoxon matched-pairs signed-rank test (comparison between CD4⁺ T and CD32^dim cells within each condition), and the ANOVA Friedman with Dunn’s multiple comparison test (comparison between different conditions of the CD4⁺ T or CD32^dim cells). Mean with SEM is represented. *p<0.05.