Table 6. Summary of ADRs.
| ADR | All (N=143) | Grade | ||
|---|---|---|---|---|
| 1 | 2 | 3 | ||
| Any ADR | 65/143 (45.5%) | 0 | 0 | 0 |
| Elevation of transaminase | 23/65 (35.4%) | 12/23 (52.2%) | 7/23 (30.4%) | 4/23 (17.4%) |
| Changes in hair color | 31/65 (47.7%) | 29/31 (93.5%) | 2/31 (6.5%) | 0 |
| Hand–foot skin reaction | 21/65 (32.3%) | 9/21 (42.9%) | 8/21 (38.1%) | 4/21 (19.0%) |
| Rash | 6/65 (9.2%) | 5/6 (83.3%) | 0 | 1/6 (16.7%) |
| Hypertension | 26/65 (40.0%) | 7/26 (26.9%) | 14/26 (53.8%) | 5/26 (19.2%) |
| Diarrhea | 26/65 (40.0%) | 14/26 (53.8%) | 8/26 (30.8%) | 4/26 (15.4%) |
| Neutrocytopenia | 8/65 (12.3%) | 2/8 (25.0%) | 4/8 (50.0%) | 2/8 (25.0%) |
| Thrombocytopenia | 7/65 (10.8%) | 4/7 (57.1%) | 3/7 (42.9%) | 0 |
| Anemia | 4/65 (6.2%) | 2/4 (50.0%) | 2/4 (50.0%) | 0 |
| Proteinuria | 25/65 (38.5%) | 14/25 (56.0%) | 8/25 (32.0%) | 3/25 (12.0%) |
| Hypothyroidism | 5/65 (7.7%) | 5/5 (100.0%) | 0 | 0 |
ADR, adverse drug reaction.