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. 2022 Jun 1;606(7913):329–334. doi: 10.1038/s41586-022-04757-3

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a, Schematic of the use of Hi-C, ChrSeq and a linkage map to transform 481 scaffolds²⁶ into a chromosome-scale genome assembly. b, Chromosomes from mitotic cells spread onto membrane slides for laser capture and sequencing. Numbers denote the identity of chromosomes present in the representative samples. c, Contact heat map of chromatin interactions indicated by Juicebox⁴; black boxes denote the four chromosomes in the final assembly. d, Linkage map generated through LinkageMapView⁶⁸, showing a lack of recombination on chromosome 1. Tick marks and labels indicate genetic markers.