Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jun 1;606(7913):329–334. doi: 10.1038/s41586-022-04757-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — a, Schematic diagram of the inferred structure of the J and V haplotypes on chromosome 1. Arrows denote putative inversions. Names, positions and sex specificity are shown for the eight genes on chromosome 1 with known key roles in the development of the reproductive system. b, Comparison of read counts for the J and V alleles of key genes in the transcriptomes of whole sexually mature worms and penis papillae (PP). Bonferroni-corrected P values from a two-sided binomial test of equal expression are shown. c, Dorsal view of control (top) and Smed-glp knockdown (bottom) sexually mature planarians. Red dashed lines and arrows indicate the posterior and anterior ends of the pharynx and the bursa canal, respectively. Scale bar, 400 um. Yellow dashed lines outline the bursa canal. d, Quantification of the length of the bursa canal relative to that of the whole worm. The y axis shows the percentage of whole-worm length spanned by the bursa canal as a box plot, with individual data points shown (n = 4 each for control and knockdown worms). Statistical significance was assessed with a two-sided, two-sample Student’s t-test (***P = 0.00029). RNAi (glp): minimum, 10.28; maximum, 11.4; median, 10.845; first quartile, 10.375; third quartile, 11.31. Control: minimum, 7.95; maximum, 8.85; median, 8.26; first quartile, 8.06; third quartile, 8.6. e, Model of negative regulation of bursa canal development by Smed-glp alleles.