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. 2022 Apr 13;606(7913):368–374. doi: 10.1038/s41586-022-04597-1

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 3 — a, Scatter bar plots show half-lives of 3BNC117 (red) and 10–1074 (blue). Each dot represents a single participant (n = 23). Bars show mean values and standard deviation. Statistical significance was determined using a two-tailed paired t-test. b, 3BNC117 (red) and 10–1074 (blue) levels in serum for Group 1 (n = 17) and Group 2 (n = 6) participants. Curves indicate mean serum antibody concentrations and error bars represent standard deviation. c, Scatter bar plots show half-lives of 3BNC117 (red) and 10–1074 (blue) separated for Group 1 (n = 17) and Group 2 (n = 6) participants. Each dot represents a single participant. Bars show mean values and standard deviation. Statistical significance was determined using a two-tailed unpaired t-test. d, 3BNC117 (red) and 10-1074 (blue) half-live comparison between individuals receiving up to 3 infusions of the combination of 3BNC117 + 10–1074¹² (n = 15) and participants receiving up to 7 infusions of the combination of 3BNC117 + 10–1074 (n = 23). Each dot represents a single participant. Bars show mean values and standard deviation. Statistical significance was determined using a two-tailed unpaired t-test.