Table 4.
Incidence of histopathological lesions in the stomach of the experimental groups.
| Lesions | Control | ASA administrated GP | SA-Tablets treated Gp | SAS-Tablets Gp | SIM Gp | |
|---|---|---|---|---|---|---|
|
Necrosis and desquamation of epithelium | - (100%) |
++++ (100%) |
++ (50%) |
+ (25%) |
- (100%) |
| Hyperemia | - (100%) |
+++ (75%) |
+++ (75%) |
++ (75%) |
- (100%) |
|
| Hemorrhage | - (100%) |
++ (100%) |
+ (25%) |
- (100%) |
- (100%) |
|
|
B. Mucosal glandular changes: |
Degeneration of the lining epithelium |
- (100%) |
+++ (50%) |
++ (50%) |
++ (25%) |
- (100%) |
| Loss of histological architecture of the glands. |
- (100%) |
+++ (50%) |
+ (25%) |
+ (25%) |
- (100%) |
|
|
C.Submucosal changes: |
Inflammatory cellular infiltration | - (100%) |
+++ (75%) |
++ (75%) |
+ (25%) |
- (100%) |
– No lesions; + slight lesions; ++ moderate lesions; +++ severe lesions; ++++ very severe lesions. Percentages represent the no. of affected rats in each group.