Effect of LEV and Sod.Se 0.25 and 0.5 mg/kg alone and in combination was tested on cognition of P0TZ-kindled rats in Y-maze test. The freely moving animals for 5 min and % spontaneous alteration was calculated. The one-way ANOVA using Dunnett’s test was used and data were expressed in mean ± S.E.M. *P < 0.05 Control vs PTZ control, ##P < 0.01 diazepam vs PTZ control, aaP < 0.01 LEV vs PTZ control, bP < 0.05 Sod.Se 0.25 vs PTZ control, cP < 0.05 Sod.Se 0.5 vs PTZ control, ddP < 0.01 LEV + Sod.Se 0.25 vs PTZ control, eeeP < 0.001 LEV + Sod.Se 0.5 vs PTZ control.