Table 1.
12 weeks WD |
BmxCre- Ackr3 fl/fl Apoe−/− |
BmxCre + Ackr3fl/fl Apoe−/− |
P value |
---|---|---|---|
Leukocytes [× 106/ml] | 1.3 ± 0.2 | 2.1 ± 0.2 | 0.011* |
Neutrophils [× 105/ml] | 3.5 ± 0.8 | 6.4 ± 0.8 | 0.017* |
Classical monocytes [× 105/ml] |
1.0 ± 0.2 | 1.2 ± 0.1 | 0.541 |
Non-classical monocytes [× 104/ml] |
8.9 ± 1.9 | 8.2 ± 1.5 | 0.776 |
B cells [× 105/ml] | 5.0 ± 1.0 | 8.2 ± 0.9 | 0.022* |
T cells [× 105/ml] | 1.8 ± 0.3 | 2.6 ± 0.3 | 0.072 |
Thrombocytes [× 103/µl] | 1118 ± 162 | 977 ± 146 | 0.523 |
Cholesterol [mg/dL] | 1208.0 ± 100.9 | 984.8 ± 144.4 | 0.219 |
Triglycerides [mg/dL] | 181.4 ± 17.8 | 132.2 ± 26.0 | 0.133 |
Bodyweight [g] | 30.7 ± 2.4 | 33.6 ± 1.7 | 0.338 |
Bold italic values are p < 0.05
Circulating leukocyte and leukocyte subset numbers quantified by flow cytometry, plasma cholesterol and triglyceride levels, as well as body weight of 12-week WD fed mice. Results represent mean ± SEM
*p < 0.05