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. 2022 Jun 8;79(7):351. doi: 10.1007/s00018-022-04369-0

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Fig. 1 — A prototypic pancreatic islet inside a semi-permeable and biocompatible membrane (PEG). This physical membrane blocks the passage to high-molecular-weight compounds (immune cells, antibodies) whilst ensuring the free release of glucose, insulin, oxygen, and nutrients necessary for the survival of the transplanted islets