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. 2022 Jun 8;79(7):351. doi: 10.1007/s00018-022-04369-0

Table 1.

In vivo applications of cell encapsulation

Polymer Encapsulated cells Application References
Natural polymers
 ALG microbeads MSCs MI [58]
 ALG-chitosan (mESCs)-derived cardiomyocytes MI [59]
NPRLCs ALF [68]
 ALG-PEG hMSCs LF [67]
 Gelatin-ALG hESC-RPE MD [15]
Synthetic polymers
 PEGDA NSCs and ECs Stroke [12]
 PVA hMSCs Bone regeneration [13]
 Star-PEG-vinylsulfone hiPSC-derived cardiomyocytes MI [19]
 PEG Dendritic cells MS [74]
 TR-ZW Islet cells T1D [40]

ALG, alginate; MSCs, mesenchymal stem cells; MI, myocardial infarcation; ALF, acute liver failure; T1D, type 1 diabetes; ALG-chitosan, Alginate-chitosan; mESCs, mouse Embryonic Stem Cells; NPRLCs, Neonatal Porcine Reaggregated Liver cells; ALG-PEG, Alginate-Poly(ethylene glycol); hMSCs, human Mesenchymal Stem Cells; hESC-RPE, human Embryonic Stem Cell-derived Retinal Pigment Epithelial Cells; MD, macular degeneration; PEGDA, Polyethylene glycol diacrylate; NSCs, Neural stem cells; EC, Endothelial cells; PVA, Poly(vinyl alcohol); hiPSC, human-Induced Pluripotent Stem Cells; PEG, Poly(ethylene glycol); MS, Multiple Sclerosis; TR-ZW, Triazole-zwitterionic polymers