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. Author manuscript; available in PMC: 2022 Jun 23.
Published in final edited form as: Mod Pathol. 2021 Dec 23;35(6):825–835. doi: 10.1038/s41379-021-00990-9

Table 1:

Patient clinicopathologic characteristics. Values are displayed as median (interquartile range) or frequency (percentage).

CHARACTERISTICS N=199
Age at Nephrectomy 65 (55, 71)
Gender
  Male 162 (81%)
  Female 37 (19%)
Tumor Size (cm) 3.5 (2.5, 5.1)
Pathologic Stage (pT 2010)
  1 163 (82%)
  2 15 (7.5%)
  3 21 (10.5%)
Type 2 Morphology
  Present (n) 95 (48%)
  % when present 25 (10, 70)
Nuclear Pseudostratification
  Present (n) 129 (65%)
  % when present 20 (10, 60)
Abundant Eosinophilic and/or Amphophilic Cytoplasm
  Present (n) 139 (70%)
  % when present 35 (10, 65)
Mitosis
  Mitotic rate ≥ 1/10 HPF 48 (24%)
  Mitotic rate when ≥ 1/10 HPF 2 (1, 3)
Necrosis 4 (0, 15)
  Present (n) 124 (62%)
  % when present 10 (5, 31)
Sarcomatoid Differentiation
  Presence (n) 4 (2%)
  % when present 7.5 (5, 10)
Sheet-like Architecture
  Presence (n) 11 (5.5%)
  % when present 10 (5, 12.5)
LVI 6 (3%)
Highest WHO/ISUP Grade
 1 34 (17%)
 2 81 (41%)
 3 80 (40%)
 4 4 (2%)
Predominant WHO/ISUP Grade
 1 120 (60%)
 2 61 (31%)
 3 18 (9%)
Highest Fuhrman Nuclear Grade
 1 45 (23%)
 2 107 (54%)
 3 43 (21%)
 4 4 (2%)
Predominant Fuhrman Nuclear Grade
 1 119 (60%)
 2 75 (37.5%)
 3 5 (2.5%)
Capsular Invasion 82 (41%)
Circumscription (%) 100 (80, 100)
Tumor Siderophages (%) 1 (0, 5)
Fibrosis (%) 5 (2, 10)
Macrophage (%) 20 (5, 40)
Papillary Adenoma(s) in Adjacent Renal Parenchyma 77 (39%)