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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: J Allergy Clin Immunol. 2021 Dec 30;149(6):1992–1997.e12. doi: 10.1016/j.jaci.2021.11.027

Figure 1. Study design.

Figure 1.

The figure on the left-hand side details the steps for identifying FHS participants from Offspring and Third Generation cohorts with and without asthma to be used in cross-sectional protein-trait association analysis. The figure on the right-hand side details the exposures (i.e., instrumental variables) and outcomes for Mendelian randomization and colocalization analyses.