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. 2022 Jun 8;13(6):537. doi: 10.1038/s41419-022-04976-6

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — A Dose–response curve of A2780 Parental vs. A2780/DDP cells (left), and HEYA8 HM vs. HEYA8 NM cells (right) against cisplatin. B Dose–response curve of miR-199a-3p-overexpressing A2780/DDP cells (left) against cisplatin and C against cisplatin/paclitaxel for SKOV-3 cells (right). The miR-199a-3p-overexpressing SKOV-3 cells were divided into two groups: cisplatin and paclitaxel treatment. D Expression of miR-199a-3p in chemosensitive vs. chemoresistant patient tumors and Kaplan–Meier Survival analysis for patient stratified by miR-199a-3p expression, and clinicopathological table of patients. Bar graph values are mean ± SD, n = 3. T-test. *P < 0.05, **P < 0.005. Statistical analysis for patient samples is mentioned in clinicopathological table.