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. Author manuscript; available in PMC: 2022 Sep 29.
Published in final edited form as: Leukemia. 2022 Mar 29;36(6):1492–1498. doi: 10.1038/s41375-022-01547-8

TABLE 1.

Capabilities of RNAseq-based DNA copy number calling algorithms

Per-sample runtime Arm/Chromosomal CNV High aneuploid adjustment Gene-level CNV
RNAseqCNV 10 minutes Yes Yes No
CNVkit 74 minutes No No Yes
CaSpER 14 minutes Yes No Yes
SuperFreq 2 hours No Yes Yes

Table notes: Per sample run time refers to average per-sample runtime on a standard PC, except SuperFreq on an high performance computing server