Skip to main content
. Author manuscript; available in PMC: 2023 Jul 1.
Published in final edited form as: Head Neck. 2022 Apr 9;44(7):1563–1575. doi: 10.1002/hed.27054

TABLE 2:

Associations of prevalence of ≥1 cardiovascular disease (CVD) clinical risk factors at baseline (at head and neck cancer diagnosis) with socio-demographic, behavioral, and cancer-related variables.

Variables ≥1 Prevalent CVD clinical risk factors (n=1441) vs none
(n=639)
Unadjusted
[OR (95% CI)]*
Adjusted
[OR (95% CI)]*
Age at HNSCC diagnosis (years)
45 or less Ref Ref
46 to <65 0.62 (0.41-0.95) 0.61 (0.40-0.93)
65 or above 0.62 (0.40-0.95) 0.62 (040-0.96)
Gender
Female Ref Ref
Male 1.11 (0.89-1.37) 1.04 (0.83-1.29)
Race
White Ref Ref
Black 0.79 (0.61-1.03) 0.71 (0.54-0.93)
Marital Status
Married/ partner Ref NA
Divorced/ separated/ widowed 0.97 (0.77-1.23)
Single 0.95 (0.75-1.20)
Geographic location (rurality)
Urban Ref Ref
Rural 0.73 (0.60-0.88) 0.70 (0.58-0.85)
HNSCC Site
Oral cavity Ref Ref
Oropharynx 1.49 (1.19-1.88) 1.50 (1.19-1.90)
Larynx 1.63 (1.27-2.10) 1.73 (1.34-2.24)
Other 1.53 (1.09-2.17) 1.64 (1.16-2.33)
Clinical Stage at diagnosis
Early (Stages 0/ I/ II) Ref NA
Advanced (III/ IV) 1.05 (0.85-1.29)
Other 0.83 (0.63-1.11)
Alcohol Use
Never Ref NA
Current 1.11 (0.92-1.35)
Former 1.27 (0.89-1.83)
Tobacco Use
Never Ref NA
Current 1.07 (0.84-1.35)
Former 0.94 (0.74-1.18)
BMI Category
Underweight/Normal Ref NA
Overweight 1.22 (0.98-1.52)
Obese 1.22 (0.97-1.55)

Notes: Abbreviations *[OR (95% CI)] = Odds ratio (95% Confidence interval), HNSCC = head neck squamous cell carcinoma, BMI = Body mass index, NA= not applicable (as not included in adjusted model); Bold= p -value ≤ 0.05.