Table 1:
CRC Patient Demographics and clinical diagnosis
| ID | Age | Gender | Race | Histology | Grade | Primary Site | Metastatic Site | Molecular profiling |
|---|---|---|---|---|---|---|---|---|
| CRC-MOS-001 | 87 | F | Caucasian | Adenocarcinoma | Moderately differentiated | Rectal | Lung | MSS |
| CRC-MOS-002 | 68 | M | Caucasian | Adenocarcinoma | Moderately differentiated | Colon | Liver | MSS, TMB 1 Muts/Mb, KRAS (G12V), APC (L674fs), p53 (I254S) |
| CRC-MOS-003 | 71 | M | Caucasian | Adenocarcinoma | Moderately differentiated | Colon | Liver | MSS, TMB 3 Mut/Mb, KRAS (G12V), APC (Q1303), SMAD4 loss, TP53 (L257Q) |
| CRC-MOS-004 | 62 | F | Caucasian | Adenocarcinoma | Moderately differentiated | Colon | Liver | MSS, TMB 3 Mut/Mb, KRAS WT APC (R1450), ATM (R805), PIK3CA (E545K) |
| CRC-MOS-005 | 73 | M | Caucasian | Adenocarcinoma | Moderately differentiated | Colon | Liver | MSS, TMB 4 Mut/Mb, KRAS (G12D), APC (R876), TP53 (R158fs), PIK3CA (E545Q) |
| CRC-MOS-006 | 31 | F | Asian | Adenocarcinoma | Poorly differentiated | Rectal | Pelvis | MSS, TMB (4 Muts/Mb) KRAS (G12D), TP53 (R175H) |
| CRC-MOS-007 | 37 | M | Caucasian | Adenocarcinoma | Colon | Liver | MSS, TMB (1 Mut/Mb), KRAS (G12D), APC (R216), TP53 (G226E) | |
| CRC-MOS-008 | 68 | M | Caucasian | Adenocarcinoma | Moderately differentiated | Colon | Liver | MSS, TMB (6 Mut/Mb) KRAS WT, APC (Q1367), EGFR amplification TP53 (R248W) |