. 2021 Sep 14;46(2):343–353. doi: 10.1007/s12639-021-01450-6

Table 4.

Acute toxicity (LD₅₀) results from oral administration

Cocktails	No of mice	Dose (mg/kg)	Weakness/reduced activity	Clogging together	Day 0 mortality	% Mortality	LD₅₀ (mg/kg)	Day 7 mortality	Day 14 mortality
Lorke’s Phase 1
CtA	3	10	No	No	0	0		0	0
	3	100	No	No	0	0		0	0
	3	1000	No	No	0	0		0	0
CtB	3	10	No	No	0	0		0	0
	3	100	No	No	0	0		0	0
	3	1000	No	No	0	0		0	0
Lorke’s phase 2
CtA	1	1600	Yes	Yes	0	0	CtA > 5000	0	0
	1	2900	Yes	Yes	0	0		0	0
	1	5000	Yes	Yes	0	0		0	0
CtB	1	1600	No	Yes	0	0	CtB > 5000	0	0
	1	2900	Yes	Yes	0	0		0	0
	1	5000	Yes	Yes	0	0		0	0