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. 2022 May 26;13:843247. doi: 10.3389/fimmu.2022.843247

Table 3.

The meta-regression analysis for the Mean Age and Publication Year to CD4 and CD8.

Predictors Number of included studies Tau2 I2 H2 R2 QM P value
Publication Year to CD4 13 15.50 92.10% 12.65 7.10% 2.19 0.14
Publication Year to CD8 13 8.24 86.23% 7.26 31.80% 5.61 0.02*
Mean Age to CD4 13 18.25 92.65% 13.60 0.00% 0.15 0.70
Mean Age to CD8 13 11.01 89.15% 9.21 8.87% 2.02 0.16

*P < 0.05; Tau2, estimated amount of residual heterogeneity; I2, residual heterogeneity or unaccounted variability; H2, unaccounted variability / sampling variability; R2, amount of heterogeneity accounted for; QM: the statistic of the test of predictors.