Figure 6.
The SimRNA High-Resolution, High-Fidelity Models of Sense LincRNA-p21 AluSx1 RNA. Figure 6 presents the high-resolution, high-fidelity sense models that have good fitting with their SAXS envelope as demonstrated by low NSD values. (A) represents model 514; (B) represents model 1036; (C) represents model 1476; (D) represents model 1677; and (E) represents model 1794 which exhibit chemically probed secondary structures: left arm (Blue); 5′-junction (Green); three-way junction (Yellow), right arm (Magenta), and the 3′-adenyl tail (Cyan). Terminal nucleotides are displayed as: 5′nt (Red, Sphere Modelled) and 3′nt (Lime Green, Sphere Modelled). Models are rotated along their x-axis by 90º as indicated by the inset. A flexible, single-stranded linker sequence is represented centrally (Orange).