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. 2022 May 25;50(10):5881–5898. doi: 10.1093/nar/gkac414

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© The Author(s) 2022. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 8. — Superimposed Overlays of Sense SAXS Envelopes with their High-Resolution, High-Fidelity SimRNA Models. Figure 8 represents the combined overlays of the sense LincRNA-p21 AluSx1 RNA envelope with their top high-resolution, SimRNA models: (A) 514; (B) 1036; (C) 1476; (D) 1677; and (E) 1794. Overall, SAXS envelopes indicate a general agreement with computationally generated structures, showing high overlap of the extended molecule with the major secondary structures identified using chemical probing techniques.