Figure 9.

Superimposed Overlays of Antisense SAXS Envelopes with their High-Resolution, High-Fidelity SimRNA Models. Figure 9 represents the combined overlays of the antisense LincRNA-p21 AluSx1 RNA envelope with their top high-resolution, SimRNA models: (A) 66; (B) 974; (C) 1013; (D) 1074; and (E) 1417. Overall, SAXS envelopes indicate a general agreement with computationally generated structures, showing high overlap of the extended molecule with the major secondary structures identified using chemical probing techniques. However, there is a slight overhang present with the right arm (Magenta) which has an area excluded from overlapping with the SAXS envelope.