Table 1.

K _M and ATPase activity profiles

	WT	E510V	Q517H
KM (3p10l-RNA)	9 ± 1 nM	13 ± 2 nM	7 ± 1 nM
KM (Cap2-10l-RNA)	61 ± 6 nM	28 ± 3 nM	21 ± 2 nM
Maximum ATPase activity (Normalized OD630)
3p10l-RNA	0.632 ± 0.020	0.551 ± 0.011	0.602 ± 0.018
Cap2-10l-RNA	0.429 ± 0.018	0.470 ± 0.006	0.594 ± 0.009
Cap2-10l/3p10l-RNA	67.9 ± 0.7%	84.6 ± 2.3%	98.7 ± 2.4%