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. 2022 May 24;50(10):5545–5564. doi: 10.1093/nar/gkac360

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© The Author(s) 2022. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 6. — Relationship between the expression of HK2 and the methylation of AHR promoter in cancer. (A) Relationship between the expression levels of HK2 and AHR retrieved in 33 different types of cancer from the TCGA. Significant correlation, Pearson r coefficient >0.3 or <–0.3 are indicated in colours (blue, negative correlation; salmon, positive correlation) (B) Relationship between the expression levels of AHR, HK2 and HK1 and the methylation level of AHR promoter in cancers. (C) Prognostic value of the AHR/HK2 axis in five different types of cancer exhibiting a negative correlation between HK2 expression and AHR promoter methylation.