TABLE 4.
The mRNA expression of EMT-related factors in mice with Gli1/Gli2 interference.
| Objects | Groups | Snail | Slug | E-cadherin | α-SMA | Vimentin |
| Mice | Normal control | 3.55 ± 0.78 | 3.00 ± 0.72 | 9.87 ± 1.04 | 2.90 ± 0.43 | 5.11 ± 1.03 |
| Model control | 8.14 ± 1.42 | 5.32 ± 1.09 | 5.12 ± 1.78 | 4.02 ± 0.87 | 5.05 ± 1.09 | |
| Gli1-shRNA | 4.33 ± 0.69a | 3.44 ± 0.59a | 6.04 ± 2.10 | 4.14 ± 1.23 | 4.45 ± 1.25 | |
| ADV-Gli1 | 9.84 ± 1.54 | 6.24 ± 1.41 | 5.41 ± 0.74 | 9.58 ± 1.73b | 6.51 ± 1.43 | |
| Gli2-shRNA | 3.73 ± 1.16a | 5.62 ± 1.75 | 10.51 ± 1.83a | 3.88 ± 1.16 | 3.56 ± 1.06a | |
| ADV-Gli2 | 15.13 ± 3.81b | 5.48 ± 0.52 | 3.06 ± 0.59b | 12.40 ± 2.44b | 8.78 ± 1.18b |
ADV, adenovirus. The sample size of each group was six cases. Values are given as the mean ± SD.
Comparison of the GLI1/GLI2-shRNA and model control groups in mice, aP < 0.05; comparison of the ADV-GLI1/GLI2 and model control groups in mice, bP < 0.05.