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Chromosomal location of human (A) ITGAV and (B) FN1 genes in chromosome 2 and chromatograms of both missense mutation sequence (wild type, heterozygote, and homozygous mutant genotypes) observed in the family. The twins are homozygous for both mutations ITGAV (c.1373G/G), FN1(c.938 G/G). Parents are heterozygous for both mutations. Nucleotide sequence Alignment and phylogenetic tree of human ITGAV and FN1 genes.
