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. 2022 Jun 1;2022:1617229. doi: 10.1155/2022/1617229

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Copyright © 2022 Yanxia Fu et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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HUC-MSCs regulate inflammatory cytokine production in colitis and colitis-related colon cancer. (a–c) HUC-MSC treatment reduced TNF-α and IL-6 while increased TGF-β1 in the serum of AOM/DSS-treated mice. (d, e) HUC-MSC treatment reduced proinflammatory cytokines produced by macrophages in serum caused by DSS. (f, g) HUC-MSC treatment reduced IFN-γ and IL-4 in serum of colitis mice. (h, i) HUC-MSC treatment reduced IL-17 while increased TGF-β1 in serum caused by DSS. Error bars: mean ± SD. ^∗p < 0.05; ^∗∗p < 0.01; ^∗∗∗p < 0.005.