Table 2.
Chi-square statistics comparing individual drugs per severity level between patient self-reporteda treatments and rheumatologist recommendations.
Treatment option | Expected rate of rheumatologist recommendation (%) | Disease severity | Chi-square (df) | P value | Reject the null hypothesis |
NSAIDb | 54 | Mild | 0.8 (1) | .36 | No |
Corticosteroids | 23 | Mild | 0.2 (1) | .62 | No |
Antimalarials | 32 | Mild | 8.8 (1) | .003 | Yes |
Immunosuppressive agents | 9 | Mild | 0.2 (1) | .67 | No |
Belimumab | 15 | Mild | 2.1 (1) | .15 | No |
Rituximab | 12 | Mild | 7.4 (1) | .007 | Yes |
NSAID | 25 | Moderate | 5.5 (1) | .02 | Yes |
Corticosteroids | 41 | Moderate | 3.1 (1) | .08 | No |
Antimalarials | 35 | Moderate | 4.5 (1) | .03 | Yes |
Immunosuppressive agents | 34 | Moderate | 9.0 (1) | .003 | Yes |
Belimumab | 35 | Moderate | 9.1 (1) | .003 | Yes |
Rituximab | 23 | Moderate | 13.7 (1) | .002 | Yes |
NSAID | 21 | Severe | 5.8 (1) | .02 | Yes |
Corticosteroids | 36 | Severe | 0.1 (1) | .75 | No |
Antimalarials | 33 | Severe | 0.7 (1) | .41 | No |
Immunosuppressive agents | 56 | Severe | 1.1 (1) | .29 | No |
Belimumab | 50 | Severe | 0.0 (1) | .99 | No |
Rituximab | 65 | Severe | 1.3 (1) | .25 | No |
All treatment options by all disease severities | N/Ac | N/Ac | 73.5 (1) | <.001 | Yes |
aIn patients who were pregnant, trying to conceive, or recently pregnant.
bNSAID: nonsteroidal anti-inflammatory drug.
cN/A: not applicable.