. 2022 Jun 6;22:101465. doi: 10.1016/j.tranon.2022.101465

Table 1.

Outcomes of EMD in various studies

Author	Patient group	Type of EMD	Survival analysis		Reference
Author	Patient group	Type of EMD	PFS	OS	Reference
Lee et al	Newly diagnosed MM with EMD(54/275)	EM-B(47),EM-S(7)	20.3 months in EMD vs. 29.1 in non-EMD(P = 0.035)	44.3 months in EMD vs. N/A in non-EMD(P = 0.006)	[9]
Pour et al	EMD at relapse(55/226)	EM-B(23),EM-S(32)	N/A	45 months in EM-B vs 30 months in EM-S(p=0.022);38 months in EMD vs.109 months in non-EMD(P<0.001)	[5]
Mangiacavalli et al	EMD at relapse(93/329)	EM-B(34),EM-S(48),both EM-B and EM-S(11)	N/A	28.8 months in EM-B vs 19.2 months in EM-S(p=0.006);24 months in EMD vs.132 months in non-EMD(P <0.001)	[93]
Beksac et al	EMD at diagnosis(130)	EM-B(38),EM-S(92)	51.7 months in EM-B vs 38.9 months in EM-S(p=0.034)	46.5 months in EM-B vs not reached in EM-S(p=0.002)	[94]
Beksac et al	EMD at relapse(96)	EM-B(12),EM-S(84)	20.9 months in EM-B vs 9.1 months in EM-S(p=0.249)	11.4 months in EM-B vs 39.8 months in EM-S(p=0.093)	[94]
Montefusco et al	Newly diagnosed MM with EMD(267/2332)	EM-B(243),EM-S(12)	25.3 months in EMD vs. 25.2 in non-EMD	63.5 months in EMD vs.79.9 in non-EMD(P = 0.01)	[95]
Kumar et al	Newly diagnosed MM with EMD(44/271)	EM-B(30),EM-S(8),both EM-B and EM-S(6)	18 months in EMD vs. 44 in non-EMD(P <0.001)	32 months in EMD vs.100 in non-EMD(P < 0.001)	[65]